Letzte Episode
Folge 2: „Diagnostik“ – Vom Symptom zur Diagnose (Episode recorded in English)
21. April 2026
Klinik und Forschung im Dialog
Gast: Prof. Dr. Sarosh Irani
Wie erkennt man Autoimmunenzephalitis im klinischen Alltag? Prof. Dr. Sarosh Irani spricht über diagnostische Denkmodelle, typische und atypische Verläufe sowie die enge Verzahnung von Forschung und Patientenversorgung. Eine Folge über klinische Erfahrung, strukturiertes Denken und die Bedeutung früher Therapieentscheidungen.
How can autoimmune encephalitis be recognised in everyday clinical practice? Prof. Dr Sarosh Irani discusses diagnostic frameworks, typical and atypical clinical courses, and the close interconnection between research and patient care. An episode focusing on clinical experience, structured thinking and the importance of early treatment decisions.
Weitere Infos:
Sarosh R. Irani, B.M., B.Ch., D.Phil. - Doctors and Medical Staff - Mayo Clinic
Deutsches Netzwerk zur Erforschung der autoimmunen Enzephalitis - GENERATE – GErman NEtwork for Research on AuToimmune Encephalitis
Models of autoantibody mediated diseases: actively nearing the human gold standard - PubMed
Permissive central tolerance plus defective peripheral checkpoints license pathogenic memory B cells in CASPR2-antibody encephalitis - PubMed
Capturing what matters: Patient-reported LGI1-ANTibody encephalitis outcome RatiNg scale (LANTERN) - PubMed
Novel risk loci in LGI1-antibody encephalitis: genome-wide association study discovery and validation cohorts - PubMed
Autoantibody-mediated central nervous system channelopathies - PubMed
Magnetic Resonance Imaging Characteristics of LGI1-Antibody and CASPR2-Antibody Encephalitis - PubMed
Ultrahigh frequencies of peripherally matured LGI1- and CASPR2-reactive B cells characterize the cerebrospinal fluid in autoimmune encephalitis - PubMed
Clinical Features and Molecular Mechanisms Underlying Autoantibody-Mediated Seizures - PubMed
Gast: Prof. Dr. Sarosh Irani
Wie erkennt man Autoimmunenzephalitis im klinischen Alltag? Prof. Dr. Sarosh Irani spricht über diagnostische Denkmodelle, typische und atypische Verläufe sowie die enge Verzahnung von Forschung und Patientenversorgung. Eine Folge über klinische Erfahrung, strukturiertes Denken und die Bedeutung früher Therapieentscheidungen.
How can autoimmune encephalitis be recognised in everyday clinical practice? Prof. Dr Sarosh Irani discusses diagnostic frameworks, typical and atypical clinical courses, and the close interconnection between research and patient care. An episode focusing on clinical experience, structured thinking and the importance of early treatment decisions.
Weitere Infos:
Sarosh R. Irani, B.M., B.Ch., D.Phil. - Doctors and Medical Staff - Mayo Clinic
Deutsches Netzwerk zur Erforschung der autoimmunen Enzephalitis - GENERATE – GErman NEtwork for Research on AuToimmune Encephalitis
Models of autoantibody mediated diseases: actively nearing the human gold standard - PubMed
Permissive central tolerance plus defective peripheral checkpoints license pathogenic memory B cells in CASPR2-antibody encephalitis - PubMed
Capturing what matters: Patient-reported LGI1-ANTibody encephalitis outcome RatiNg scale (LANTERN) - PubMed
Novel risk loci in LGI1-antibody encephalitis: genome-wide association study discovery and validation cohorts - PubMed
Autoantibody-mediated central nervous system channelopathies - PubMed
Magnetic Resonance Imaging Characteristics of LGI1-Antibody and CASPR2-Antibody Encephalitis - PubMed
Ultrahigh frequencies of peripherally matured LGI1- and CASPR2-reactive B cells characterize the cerebrospinal fluid in autoimmune encephalitis - PubMed
Clinical Features and Molecular Mechanisms Underlying Autoantibody-Mediated Seizures - PubMed
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