Pathophysiologie der Autoimmunenzephalitis
Gast: Prof. Dr. Christian Geis
Wie greifen Autoantikörper in synaptische Prozesse ein? Prof. Dr. Christian Geis erläutert die molekularen Mechanismen der Autoimmunenzephalitis, von Rezeptorveränderungen bis zur Netzwerkdysfunktion. Diese Folge schlägt die Brücke zwischen Immunreaktion, Synapse und klinischem Symptom.
Weitere Infos:
https://www.uniklinikum-jena.de/neuro/
Sektion Translationale Neuroimmunologie
Deutsches Netzwerk zur Erforschung der autoimmunen Enzephalitis - GENERATE – GErman NEtwork for Research on AuToimmune Encephalitis
GENERATE-BOOST: Neue Behandlungsstudie für autoimmune Gehirnentzündung
BOOST - GENERATE – GErman NEtwork for Research on AuToimmune Encephalitis
Reduced Hospital Incidence of Autoimmune Encephalitis During the COVID-19 Pandemic - PubMed
Anti-CD19 CAR-T cells are effective in severe idiopathic Lambert-Eaton myasthenic syndrome - PubMed
Human NMDAR autoantibodies disrupt excitatory-inhibitory balance, leading to hippocampal network hypersynchrony - PubMed
Comparative Effects of Domain-Specific Human Monoclonal Antibodies Against LGI1 on Neuronal Excitability - PubMed
Autoimmune encephalitis: novel therapeutic targets at the preclinical level - PubMed
Generate-Boost: study protocol for a prospective, multicenter, randomized controlled, double-blinded phase II trial to evaluate efficacy and safety of bortezomib in patients with severe autoimmune encephalitis - PubMed
LGI1 antibodies alter Kv1.1 and AMPA receptors changing synaptic excitability, plasticity and memory - PubMed
Gast: Prof. Dr. Christian Geis
Wie greifen Autoantikörper in synaptische Prozesse ein? Prof. Dr. Christian Geis erläutert die molekularen Mechanismen der Autoimmunenzephalitis, von Rezeptorveränderungen bis zur Netzwerkdysfunktion. Diese Folge schlägt die Brücke zwischen Immunreaktion, Synapse und klinischem Symptom.
Weitere Infos:
https://www.uniklinikum-jena.de/neuro/
Sektion Translationale Neuroimmunologie
Deutsches Netzwerk zur Erforschung der autoimmunen Enzephalitis - GENERATE – GErman NEtwork for Research on AuToimmune Encephalitis
GENERATE-BOOST: Neue Behandlungsstudie für autoimmune Gehirnentzündung
BOOST - GENERATE – GErman NEtwork for Research on AuToimmune Encephalitis
Reduced Hospital Incidence of Autoimmune Encephalitis During the COVID-19 Pandemic - PubMed
Anti-CD19 CAR-T cells are effective in severe idiopathic Lambert-Eaton myasthenic syndrome - PubMed
Human NMDAR autoantibodies disrupt excitatory-inhibitory balance, leading to hippocampal network hypersynchrony - PubMed
Comparative Effects of Domain-Specific Human Monoclonal Antibodies Against LGI1 on Neuronal Excitability - PubMed
Autoimmune encephalitis: novel therapeutic targets at the preclinical level - PubMed
Generate-Boost: study protocol for a prospective, multicenter, randomized controlled, double-blinded phase II trial to evaluate efficacy and safety of bortezomib in patients with severe autoimmune encephalitis - PubMed
LGI1 antibodies alter Kv1.1 and AMPA receptors changing synaptic excitability, plasticity and memory - PubMed
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